Check before you leave that you have your ATM card and Credit Cards
Pack light (Bottled water and snacks, Medications, Toiletries/Make-Up, etc.)
Find a list of interesting places and attractions to visit along the route.
Travel documents and maps. Help plan your trip and rest areas.
Have a pre-packed toiletries kit readily available that includes travel-size items of things like toothpaste, skin lotions and contact lens solutions Cellular telephones are always handy.
Internet Access with friends and relatives. Watch for those internet cafe's and hotels with internet access.
Music for the trip or audio cassettes work well for those quite moments.